Article
Associations of non-pedunculated T1 colorectal adenocarcinoma outcome with consensus molecular subtypes, immunoscore, and microsatellite status: a multicenter case-cohort study.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Dec 2020
Haasnoot Krijn J C, Backes Yara, Moons Leon M G, Kranenburg Onno, Trinh Anne, Vermeulen Louis, Noë Michaël, Tuynman Jurriaan B, van Lent Anja U G, van Ginneken Rosaline, Seldenrijk Cornelis A, Raicu Mihaela G, Trumpi Kari, Ubink Inge, Milne Anya N, Boonstra Jurjen J, Groen John N, Schwartz Matthijs P, Wolfhagen Frank H J, Geesing Joost M J, Ter Borg Frank, Brosens Lodewijk A A, van Bergeijk Jeroen, Spanier Bernhard W M, de Vos Tot Nederveen Cappel Wouter H, Kessels Koen, Seerden Tom C J, Vleggaar Frank P, Offerhaus G Johan A, Siersema Peter D, Elias Sjoerd G, Laclé Miangela M
Abstract excerpt
Advanced colorectal cancer (CRC) consensus molecular subtype 4 (CMS4) or CRC with a low immunoscore is associated with shorter survival times. Non-metastatic CRC with microsatellite instability (MSI) is associated with a lower risk of recurrence. We evaluated outcome (lymph node metastases [LNM] or cancer recurrence) in these tumor subtypes in patients with surgically-removed non-pedunculated T1 CRC by performing...
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