Article
Four cypermethrin isomers induced stereoselective metabolism in H295R cells.
Chirality - 1 Aug 2020
Ji Chenyang, Yu Chang, Zhu Jianqiang, Cheng Yafei, Tian Tian, Zhou Bingqi, Gu Jinping, Fan Jun, Zhao Meirong
Abstract excerpt
Cypermethrin (CP) is widely used for controlling agricultural and indoor vermin. Previous studies have reported the stereoselective difference of CP in biological activities. However, little is known about their potential mechanisms between metabolic phenotypes and endocrine-disrupting effects. Herein, nuclear magnetic resonance (NMR)-based metabolomics combining metabolite identification and pathway analysis...
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