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Article

Donor Klotho KL-VS Polymorphism Predicts Allograft Glomerulosclerosis and Early Post-Transplant Kidney Function.

Transplantation proceedings - 1 Oct 2020

Pazik Joanna, Rembek Karolina, Sadowska-Jakubowicz Anna, Sitarek Elżbieta, Kosieradzki Maciej, Durlik Magdalena

Abstract excerpt

BACKGROUND: The Klotho protein, encoded by the KL (Klotho) gene, exerts antiaging and antifibrotic effects. The KL-VS genotype diminishes Klotho expression and correlates with cardiovascular death, heart failure, and chronic kidney disease progression. The aim of this study was to analyze the contribution of donor Klotho rs9536314 and rs9527025 polymorphisms (KL-VS genotype) to renal allograft morphology and...

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Identifiers

PMID: 32571701
DOI: 10.1016/j.transproceed.2020.02.086

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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