Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Replication origin location might contribute to genetic variability in Trypanosoma cruzi.

BMC genomics - 22 Jun 2020

de Araujo Christiane Bezerra, da Cunha Julia Pinheiro Chagas, Inada Davi Toshio, Damasceno Jeziel, Lima Alex Ranieri Jerônimo, Hiraiwa Priscila, Marques Catarina, Gonçalves Evonnildo, Nishiyama-Junior Milton Yutaka, McCulloch Richard, Elias Maria Carolina

Abstract excerpt

BACKGROUND: DNA replication in trypanosomatids operates in a uniquely challenging environment, since most of their genomes are constitutively transcribed. Trypanosoma cruzi, the etiological agent of Chagas disease, presents high variability in both chromosomes size and copy number among strains, though the underlying mechanisms are unknown. RESULTS: Here we have mapped sites of DNA replication initiation across...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Composition
Share to DNA, Protozoan

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Replication

Share to High-Throughput Nucleotide Sequencing

Share to Replication Origin

Share to Triatoma

Share to Trypanosoma cruzi

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 32571205
DOI: 10.1186/s12864-020-06803-8
PMCID: PMC7310030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Replication origin location might contribute to genetic variability in Trypanosoma cruzi.PMID 32571205Read ↗

Integrating high-throughput analysis to create an atlas of replication origins in Trypanosoma cruzi in the context of genome structure and variabilitySemantic proximity Read ↗

Genome-wide Analysis Reveals Extensive Functional Interaction between DNA Replication Initiation and Transcription in the Genome of Trypanosoma bruceiSemantic proximity Read ↗

Trypanosoma cruzi Has 32 Chromosomes: A Telomere-to-Telomere Assembly Defines Its Karyotype.Semantic proximity Read ↗

Nuclear DNA Replication in Trypanosomatids: There Are No Easy Methods for Solving Difficult ProblemsSemantic proximity Read ↗

The genome and its implications.Semantic proximity Read ↗

A genomic scale map of genetic diversity in Trypanosoma cruzi.Semantic proximity Read ↗

The complete genome of Trypanosoma cruzi reveals 32 chromosomes and three genomic compartmentsSemantic proximity Read ↗

Anatomy and evolution of telomeric and subtelomeric regions in the human protozoan parasite Trypanosoma cruziSemantic proximity Read ↗

Chromosomal copy number variation reveals differential levels of genomic plasticity in distinct Trypanosoma cruzi strains.Semantic proximity Read ↗

Strain-specific genome evolution in Trypanosoma cruzi, the agent of Chagas disease.Semantic proximity Read ↗

A phased genome assembly of a Colombian Trypanosoma cruzi TcI strain and the evolution of gene familiesSemantic proximity Read ↗

Hidden origami in <i>Trypanosoma cruzi</i> nuclei highlights its nonrandom 3D genomic organizationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.