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A phased genome assembly of a Colombian Trypanosoma cruzi TcI strain and the evolution of gene families

24 Jan 2024

Abstract excerpt

Chagas is an endemic disease in tropical regions of Latin America, caused by the parasite Trypanosoma cruzi. High intraspecies variability and genome complexity have been challenges to assemble high quality genomes needed for studies in evolution, population genomics, diagnosis and drug development. Here we present a chromosome-level phased assembly of a TcI T. cruzi strain (Dm25). While 29 chromosomes show a...

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PMID: 38267502
DOI: 10.1038/s41598-024-52449-x

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