Article
Cerebrospinal Fluid YKL-40 and Neurogranin in Familial Alzheimer's Disease: A Pilot Study.
Journal of Alzheimer's disease : JAD - 1 Jan 2020
Thordardottir Steinunn, Almkvist Ove, Johansson Charlotte, Zetterberg Henrik, Blennow Kaj, Graff Caroline
Abstract excerpt
BACKGROUND: YKL-40 and neurogranin are promising additional cerebrospinal fluid (CSF) biomarkers for Alzheimer's disease (AD) which reflect different underlying disease mechanisms. OBJECTIVE: To compare the levels of CSF YKL-40 and neurogranin between asymptomatic carriers of familial AD (FAD) mutations (MC) and non-carriers (NC) from the same families. Another objective was to assess changes in YKL-40 and...
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