Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CFTR modulator therapies - Effect on life expectancy in people with cystic fibrosis.

Paediatric respiratory reviews - 1 Jun 2022

Balfour-Lynn I M, King J A

Abstract excerpt

CFTR modulators have dramatically changed the clinical course of CF in those fortunate enough to receive them. Inevitably, randomised controlled trials during the development of these drugs are too short to use mortality as an outcome. Evidence for their effect on life expectancy are best gained from real world registry studies specifically looking at mortality, but these are only available for ivacaftor to date....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aminophenols
Share to Cystic Fibrosis
Share to Cystic Fibrosis Transmembrane Conductance Regulator

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Life Expectancy

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 32565113
DOI: 10.1016/j.prrv.2020.05.002
PMCID: PMC7255286

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CFTR modulator therapies - Effect on life expectancy in people with cystic fibrosis.PMID 32565113Read ↗

CFTR modulator therapy: transforming the landscape of clinical care in cystic fibrosis.Semantic proximity Read ↗

CFTR Modulators in People with Cystic Fibrosis: Real-World Evidence in FranceSemantic proximity Read ↗

An Update on CFTR Modulators as New Therapies for Cystic Fibrosis.Semantic proximity Read ↗

Review of CFTR modulators 2020.Semantic proximity Read ↗

Real world outcomes of CFTR modulator therapy in Australian adults and children.Semantic proximity Read ↗

Optimising the care and quality of life of people with cystic fibrosis: the influence of cystic fibrosis transmembrane conductance regulator modulators.Semantic proximity Read ↗

Update on Clinical Outcomes of Highly Effective Modulator Therapy.Semantic proximity Read ↗

CFTR modulator monotherapy for people with cystic fibrosis with class II CFTR gene variants (most commonly F508del).Semantic proximity Read ↗

Impact of novel CFTR modulator on sinonasal quality of life in adult patients with cystic fibrosis.Semantic proximity Read ↗

Calibration and validation of modeled 5-year survival predictions among people with cystic fibrosis treated with the cystic fibrosis transmembrane conductance regulator modulator ivacaftor using United States registry data.Semantic proximity Read ↗

A survey: Understanding the health and perspectives of people with CF not benefiting from CFTR modulators.Semantic proximity Read ↗

Patients with cystic fibrosis who could not receive the CFTR modulator treatment: What did they lose in 1 year?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.