Article
Unique Bipolar Gene Architecture in the RNA Genome of Influenza A Virus.
Biochemistry. Biokhimiia - 1 Mar 2020
Zhirnov O P
Abstract excerpt
The genome of influenza A virus consists of eight single-stranded negative-polarity RNA segments. The eighth segment (NS) encodes the anti-interferon protein NS1 (27 kDa) and the nuclear export protein NEP (14 kDa) via the classic negative-sense strategy. It also contains an additional positive-sense open reading frame that can be directly translated into the negative strand protein 8 (NSP8; 18-25 kDa in...
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