Article
The Role of LAM Genes in the Pheromone-Induced Cell Death of S. cerevisiae Yeast.
Biochemistry. Biokhimiia - 1 Mar 2020
Sokolov S S, Galkina K V, Litvinova E A, Knorre D A, Severin F F
Abstract excerpt
Lam1-4 proteins perform non-vesicular transport of sterols from the plasma membrane to the endoplasmic reticulum. Disruption of their function leads to an increase in the content of sterols in the plasma membrane. In mammals, homologs of Lam proteins are responsible for the internalization of plasma cholesterol. The biological role of Lam proteins in yeast remains unclear, since the strains lacking individual LAM...
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