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Article

EMT and EndMT: Emerging Roles in Age-Related Macular Degeneration

16 Jun 2020

Abstract excerpt

Epithelial-mesenchymal transition (EMT) and endothelial-mesenchymal transition (EndMT) are physiological processes required for normal embryogenesis. However, these processes can be hijacked in pathological conditions to facilitate tissue fibrosis and cancer metastasis. In the eye, EMT and EndMT play key roles in the pathogenesis of subretinal fibrosis, the end-stage of age-related macular degeneration (AMD) that...

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PMID: 32560057
DOI: 10.3390/ijms21124271

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