Genetic control of C3 production by the S region of the mouse MHC.

doi:10.1111/j.1744-313x.1988.tb00437.x

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Article

Genetic control of C3 production by the S region of the mouse MHC.

Journal of immunogenetics - 1 Jan 2000

Dieli F, Lio D, Sireci G, Salerno A

Abstract excerpt

The present paper reports evidence indicating that the level of the third complement component (C3) is regulated by the S region of the murine H-2 complex. In fact, using congenic strains of mice we demonstrate that mice with the k haplotype at the S region show high C3 levels, whereas mice with...

Topics

Alleles
Animals
Complement C3
Gene Expression Regulation
H-2 Antigens
Haplotypes
Hemolysis
Major Histocompatibility Complex
Male
Mice
Mice, Inbred Strains

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