Article
Patient genetics is linked to chronic wound microbiome composition and healing.
PLoS pathogens - 1 Jun 2020
Tipton Craig D, Wolcott Randall D, Sanford Nicholas E, Miller Clint, Pathak Gita, Silzer Talisa K, Sun Jie, Fleming Derek, Rumbaugh Kendra P, Little Todd D, Phillips Nicole, Phillips Caleb D
Abstract excerpt
The clinical importance of microbiomes to the chronicity of wounds is widely appreciated, yet little is understood about patient-specific processes shaping wound microbiome composition. Here, a two-cohort microbiome-genome wide association study is presented through which patient genomic loci associated with chronic wound microbiome diversity were identified. Further investigation revealed that alternative TLN2...
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