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LncRNA SNHG16 facilitates the liver metastasis of colorectal cancer by modulating circulating tumor cell epithelial-mesenchymal transition via a positive feedback loop with the YAP1/TEAD1 complex

2022-09-08

Abstract excerpt

<h4>Background: </h4> Circulating tumor cells (CTCs) are important precursors of colorectal cancer (CRC) metastasis. The epithelial-mesenchymal transition (EMT) process facilitates CTC invasion by allowing these cells to evade antimetastatic checkpoints to mediate distant metastasis. However, the molecular mechanism of CTC EMT remains largely unknown. <h4>Results: </h4> Here, we studied the oncogenic long noncodi...

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Literature Corpus work
1a3660f8-bff8-5bed-bcbc-829964fa00b0
DOI
10.21203/rs.3.rs-1122369/v1
Open publication

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LncRNA SNHG16 facilitates the liver metastasis of colorectal cancer by modulating circulating tumor cell epithelial-mesenchymal transition via a positive feedback loop with the YAP1/TEAD1 complexDOI 10.21203/rs.3.rs-1122369/v1
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