Article
Regulation of mesenchymal phenotype by MicroRNAs in cancer.
Current cancer drug targets - 1 Nov 2013
Yan Jinchun, Gumireddy Kiranmai, Li Anping, Huang Qihong
Abstract excerpt
Epithelial-mesenchymal transition (EMT) is a developmental process that converts epithelial cells into migratory and invasive cells. This process also plays an important role in cancer progression and metastasis by enabling tumor cells to leave primary sites. EMT is regulated by complex transcription networks and post-transcriptional modulators. MicroRNAs are single-stranded non-coding RNAs that represent a novel...
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