Article
Expression of microRNAs in human platelet-poor plasma: analysis of the factors affecting their expression and association with proximal genetic variants.
Epigenetics - 1 Dec 2020
Rodriguez-Rius Alba, Martinez-Perez Angel, López Sonia, Sabater-Lleal Maria, Souto Juan Carlos, Soria José Manuel
Abstract excerpt
To translate circulating microRNAs (miRNAs) into the clinic, a deeper understanding of the factors affecting their expression is needed. In this study, we explored the features affecting the expression of miRNAs and their genetic regulation using the expression data of 103 miRNAs obtained by qPCR in the platelet-poor plasma of 104 subjects. The principal components (PCs) of the expression of the miRNAs were...
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