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H. pylori infection alters repair of DNA double-strand breaks via SNHG17

14 Jun 2020

Abstract excerpt

Chronic infections can lead to carcinogenesis through inflammation-related mechanisms. Chronic infection of the human gastric mucosa with Helicobacter pylori is a well-known risk factor for gastric cancer. However, the mechanisms underlying H. pylori-induced gastric carcinogenesis are incompletely defined. We aimed to screen and clarify the functions of long noncoding RNAs (lncRNAs) that are differentially...

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PMID: 32538894
DOI: 10.1172/jci125581

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