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Article

Human Norovirus Replication in Temperature-Optimized MDCK Cells by Forkhead Box O1 Inhibition.

Journal of microbiology and biotechnology - 28 Sept 2020

Jeong Eun-Hye, Cho Se-Young, Vaidya Bipin, Ha Sang Hoon, Jun Sangmi, Ro Hyun-Joo, Lee Yujeong, Lee Juhye, Kwon Joseph, Kim Duwoon

Abstract excerpt

Human noroviruses (HuNoVs) are a leading cause of gastroenteritis outbreaks worldwide. However, the paucity of appropriate cell culture model for HuNoV replication has prevented developing effective anti-HuNoV therapy. In this study, first, the replication of the virus at various temperatures in different cells was compared, which showed that lowering the culture temperature from 37°C significantly increased...

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Identifiers

PMID: 32522961
DOI: 10.4014/jmb.2003.03071
PMCID: PMC9745657

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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