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Article

Loss of CNDP causes a shorter lifespan and higher sensitivity to oxidative stress in Drosophila melanogaster.

Biomedical research (Tokyo, Japan) - 1 Jan 2020

Yamakawa-Kobayashi Kimiko, Ohhara Yuya, Kawashima Takumi, Ohishi Yoshitatsu, Kayashima Yasunari

Abstract excerpt

Increasing oxidative stress seems to be the result of an imbalance between free radical production and antioxidant defenses. During the course of aging, oxidative stress causes tissue/cellular damage, which is implicated in numerous age-related diseases. Carnosinase (CN or CNDP) is dipeptidase, which is associated with carnosine and/or glutathione (GSH) metabolism, those are the most abundant naturally occurring...

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PMID: 32522930
DOI: 10.2220/biomedres.41.131

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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