Article
A genetic polymorphism of IL17F rs763780 associated with anti-E production in the Han Chinese population.
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis - 1 Aug 2020
Chen Sitian, Xiao Jie, Song Ning, Xu Haixia, Tian Li, Liu Zhong
Abstract excerpt
OBJECTIVE: This study aimed to investigate the association among 4 single nucleotide polymorphisms (SNPs) in the genes TLR3, IL17F, ERAP1 and ERAP2 with anti-E alloantibody production. BACKGROUND: Anti-E alloantibodies can lead to clinically significant delayed hemolytic transfusion reactions (DHTRs) and hemolytic disease of the newborn (HDN). Some individuals produce anti-E alloantibodies post- transfusion. The...
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