Article
Duplication and diversification of a unique chromosomal virulence island hosting the subtilase cytotoxin in Escherichia coli ST58.
Microbial genomics - 1 Jun 2020
Wyrsch Ethan R, Chowdhury Piklu Roy, Jarocki Veronica M, Brandis Kate J, Djordjevic Steven P
Abstract excerpt
The AB5 cytotoxins are important virulence factors in Escherichia coli. The most notable members of the AB5 toxin families include Shiga toxin families 1 (Stx1) and 2 (Stx2), which are associated with enterohaemorrhagic E. coli infections causing haemolytic uraemic syndrome and haemorrhagic colitis. The subAB toxins are the newest and least well understood members of the AB5 toxin gene family. The subtilase toxin...
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