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Article

A New Family of Potent AB5 Cytotoxins Produced by Shiga Toxigenic <i>Escherichia coli </i>

28 Jun 2004

Abstract excerpt

The Shiga toxigenic Escherichia coli (STEC) O113:H21 strain 98NK2, which was responsible for an outbreak of hemolytic uremic syndrome, secretes a highly potent and lethal subtilase cytotoxin that is unrelated to any bacterial toxin described to date. It is the prototype of a new family of AB(5) toxins, comprising a single 35-kilodalton (kD) A subunit and a pentamer of 13-kD B subunits. The A subunit is a...

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Identifiers

PMID: 15226357
DOI: 10.1084/jem.20040392

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A New Family of Potent AB5 Cytotoxins Produced by Shiga Toxigenic <i>Escherichia coli </i>PMID 15226357Read ↗

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