Article
Biological Factors behind Melanoma Response to Immune Checkpoint Inhibitors.
International journal of molecular sciences - 6 Jun 2020
Olbryt Magdalena, Rajczykowski Marcin, Widłak Wiesława
Abstract excerpt
Modern immunotherapy together with targeted therapy has revolutionized the treatment of advanced melanoma. Inhibition of immune checkpoints significantly improved the median overall survival and gave hope to many melanoma patients. However, this treatment has three serious drawbacks: high cost, serious side effects, and an effectiveness limited only to approximately 50% of patients. Some patients do not derive...
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