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Article

Molecular variation of Plasmodium vivax dehydrofolate reductase in Mexico and Nicaragua contrasts with that occurring in South America.

Salud publica de Mexico - 1 Jan 2000

González-Cerón Lilia, Rodríguez Mario H, Montoya Alberto, Santillán-Valenzuela Frida, Corzo-Gómez Josselin C

Abstract excerpt

OBJECTIVE: To research mutations associated to pyrimethamine resistance in dihydrofolate reductase (pvdhfr) of Plasmodium vivax from Mexico and Nicaragua and compare it to that reported in the rest of America. MATERIALS AND METHODS: Genomic DNA was obtained from P. vivax-infected blood samples. A pvdhfr gene fragment was amplified and sequenced. The identified gene variations were compared to those observed in...

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PMID: 32516871
DOI: 10.21149/10129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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