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Article

Molecular analysis of chloroquine and sulfadoxine-pyrimethamine resistance-associated alleles in Plasmodium falciparum isolates from Nicaragua.

The American journal of tropical medicine and hygiene - 1 May 2014

Sridaran Sankar, Rodriguez Betzabe, Soto Aida Mercedes, Macedo De Oliveira Alexandre, Udhayakumar Venkatachalam

Abstract excerpt

Chloroquine (CQ) is used as a first-line therapy for the treatment of Plasmodium falciparum malaria in Nicaragua. We investigated the prevalence of molecular markers associated with CQ and sulfadoxine-pyrimethamine (SP) resistance in P. falciparum isolates obtained from the North Atlantic Autonomous Region of Nicaragua. Blood spots for this study were made available from a CQ and SP drug efficacy trial conducted...

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Identifiers

PMID: 24615126
DOI: 10.4269/ajtmh.13-0214
PMCID: PMC4015575

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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