Article
The mechanoelectrical transducer channel is not required for regulation of cochlear blood flow during loud sound exposure in mice.
Scientific reports - 8 Jun 2020
Burwood George W S, Dziennis Suzan, Wilson Teresa, Foster Sarah, Zhang Yuan, Liu Gangjun, Yang Jianlong, Elkins Sean, Nuttall Alfred L
Abstract excerpt
The mammalian cochlea possesses unique acoustic sensitivity due to a mechanoelectrical 'amplifier', which requires the metabolic support of the cochlear lateral wall. Loud sound exposure sufficient to induce permanent hearing damage causes cochlear blood flow reduction, which may contribute to hearing loss. However, sensory epithelium involvement in the cochlear blood flow regulation pathway is not fully...
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