Article
Increased Proinflammatory Cytokine Production by Chronic Hepatitis B Patients with Mutant Hepatitis B Virus: Plausible Mechanisms Underlying Severe Liver Diseases in These Patients.
Viral immunology - 1 Sept 2020
Raihan Ruksana, Akbar Sheikh Mohammad Fazle, Al Mahtab Mamun, Khan Md Sakirul Islam, Tabassum Shahina, Tee Kok Keng, Mohamed Rosmawati Binti
Abstract excerpt
Hepatitis B virus (HBV) is a noncytopathic virus and billions of HBV-infected patients live uneventful lives and do not suffer from notable liver damage. However, HBV also causes progressive liver diseases characterized by hepatic inflammation, hepatic fibrosis, and liver cancer in millions of HBV-infected patients. The goal of this study was to evaluate the role of mutant HBV in HBV pathogenesis. In a cohort of...
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