Article
Optimal processing for proteomic genotyping of single human hairs.
Forensic science international. Genetics - 1 Jul 2020
Goecker Zachary C, Salemi Michelle R, Karim Noreen, Phinney Brett S, Rice Robert H, Parker Glendon J
Abstract excerpt
The use of hair evidence for human identification is undergoing considerable improvement through the adoption of proteomic genotyping. Unlike traditional microscopic comparisons, protein sequencing provides quantitative and empirically based estimates for random match probability. Non-synonymous SNPs are translated as single amino acid polymorphisms and result in genetically variant peptides. Using high...
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