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Article

Elucidation of familial relationships using hair shaft proteomics.

Forensic science international. Genetics - 1 Sept 2021

Karim Noreen, Plott Tempest J, Durbin-Johnson Blythe P, Rocke David M, Salemi Michelle, Phinney Brett S, Goecker Zachary C, Pieterse Marc J M, Parker Glendon J, Rice Robert H

Abstract excerpt

This study examines the potential of hair shaft proteomic analysis to delineate genetic relatedness. Proteomic profiling and amino acid sequence analysis provide information for quantitative and statistically-based analysis of individualization and sample similarity. Protein expression levels are a function of cell-specific transcriptional and translational programs. These programs are greatly influenced by an...

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PMID: 34315035
DOI: 10.1016/j.fsigen.2021.102564

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