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Proteomic genotyping: Using mass spectrometry to infer SNP genotypes in pigmented and non-pigmented hair.

Forensic science international - 1 May 2020

Franklin Rachel N, Karim Noreen, Goecker Zachary C, Durbin-Johnson Blythe P, Rice Robert H, Parker Glendon J

Abstract excerpt

Proteomic genotyping uses genetically variant peptides that contain single amino acid polymorphisms to infer the genotype of corresponding non-synonymous SNP alleles. We have focused on hair proteins as a source of protein-based genetic information in a forensic context. An optimized sample processing protocol for hair shafts has been developed for use on a single hair that allows us to conduct validation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32182563
DOI: 10.1016/j.forsciint.2020.110200

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