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Long-Term Outcomes of Genetic Parkinson’s Disease

29 May 2020

Abstract excerpt

Parkinson's disease (PD) is a progressive neurodegenerative disorder that affects 1-2% of people by the age of 70 years. Age is the most important risk factor, and most cases are sporadic without any known environmental or genetic causes. Since the late 1990s, mutations in the genes SNCA, PRKN, LRRK2, PINK1, DJ-1, VPS35, and GBA have been shown to be important risk factors for PD. In addition, common variants...

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PMID: 32498494
DOI: 10.14802/jmd.19080

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