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Article

Sp1-mediated up-regulation of lnc00152 promotes invasion and metastasis of retinoblastoma cells via the miR-30d/SOX9/ZEB2 pathway

1 Jun 2020

Abstract excerpt

PURPOSE: Previously, we found that long non-coding RNA (lncRNA) MEG3 may act as a tumour suppressor in retinoblastoma. Overall, however, little is known about the role of lncRNAs in retinoblastoma. Here, we aimed to determine the expression and clinical significance of lnc00152 in retinoblastoma. METHODS: Lnc00152 and its downstream targets were selected using GEO datasets. The level of lnc00152 in primary...

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PMID: 32488851
DOI: 10.1007/s13402-020-00522-8

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