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Article

LncRNA TMPO-AS1 up-regulates the expression of HIF-1α and promotes the malignant phenotypes of retinoblastoma cells via sponging miR-199a-5p.

Pathology, research and practice - 1 Apr 2020

Peng Xifeng, Yan Jian, Cheng Fang

Abstract excerpt

BACKGROUND: Long non-coding RNA (lncRNA) TMPO antisense RNA 1 (TMPO-AS1) is reported to be oncogenic in prostate cancer and lung cancer. This study aims to investigate the expression and biological function of it in retinoblastoma (RB), and explore its regulatory role for miR-199a-5p and hypoxia-inducible factor-1α (HIF-1α). METHODS: Paired RB samples were collected, and the expression levels of TMPO-AS1,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32139259
DOI: 10.1016/j.prp.2020.152853

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