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Article

MetaCNV - a consensus approach to infer accurate copy numbers from low coverage data.

BMC medical genomics - 1 Jun 2020

Friedrich Stefanie, Barbulescu Remus, Helleday Thomas, Sonnhammer Erik L L

Abstract excerpt

BACKGROUND: The majority of copy number callers requires high read coverage data that is often achieved with elevated material input, which increases the heterogeneity of tissue samples. However, to gain insights into smaller areas within a tissue sample, e.g. a cancerous area in a heterogeneous tissue sample, less material is used for sequencing, which results in lower read coverage. Therefore, more focus needs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32487140
DOI: 10.1186/s12920-020-00731-y
PMCID: PMC7268502

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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