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DNA damage in testicular germ cells and spermatozoa. When and how is it induced? How should we measure it? What does it mean?

6 Jan 2023

Abstract excerpt

This review surveys the causes and consequences of DNA damage in the male germ line from spermatogonial stem cells to fully differentiated spermatozoa. Within the stem cell population, DNA integrity is well maintained as a result of excellent DNA surveillance and repair; however, a progressive increase in background mutation rates does occur with paternal age possibly as a result of aberrant DNA repair as well as...

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PMID: 36604857
DOI: 10.1111/andr.13375

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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