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Article

Natural cryptic variation in epigenetic modulation of an embryonic gene regulatory network

1 Jun 2020

Abstract excerpt

wild isotypes, owing to rapid developmental system drift driven by accumulation of cryptic genetic variants. We report here that heritable epigenetic factors that are stimulated by transient developmental diapause also underlie cryptic variation in the requirement for SKN-1 in endoderm development. This epigenetic memory is inherited from the maternal germline, apparently through a nuclear, rather than...

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PMID: 32482879
DOI: 10.1073/pnas.1920343117

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