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Article

Epigenetic resolution of the 'curse of complexity' in adaptive evolution of complex traits.

The Journal of physiology - 1 Jun 2014

Badyaev Alexander V

Abstract excerpt

The age of most genes exceeds the longevity of their genomic and physiological associations by many orders of magnitude. Such transient contexts modulate the expression of ancient genes to produce currently appropriate and often highly distinct developmental and functional outcomes. The efficacy of such adaptive modulation is diminished by the high dimensionality of complex organisms and associated vast areas of...

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Identifiers

PMID: 24882810
DOI: 10.1113/jphysiol.2014.272625
PMCID: PMC4048085

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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