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Culturing and Manipulating Mouse Embryonic Stem Cells.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2020

Kioussi Chrissa

Abstract excerpt

Mouse embryonic stem cells (mESC) have the ability to self-renew due to their rapid proliferation and high telomerase activity while maintaining their pluripotency. Depending on the environment, mESC can differentiate into a broad range of cell types. These characteristics have established mESC as a tool for modeling human disease, genetic engineering, lineage specificity, stem cell-based therapies, and tissue...

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PMID: 32474863
DOI: 10.1007/978-1-0716-0655-1_1

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