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Article

Reduced sensitivity for EGFR T790M mutations using the Idylla EGFR Mutation Test.

Journal of clinical pathology - 1 Jan 2021

Lee Eric, Jones Victoria, Topkas Eleni, Harraway James

Abstract excerpt

AIMS: Osimertinib is a third-generation EGFR (epidermal growth factor receptor) tyrosine kinase inhibitor that is effective in non-small cell lung cancer (NSCLC) harbouring the EGFR T790M mutation. The Idylla EGFR Mutation Test is a rapid cartridge-based method for detecting T790M and other EGFR mutations. However, false negative T790M results have been reported, and the sensitivity of the assay for this mutation...

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Identifiers

PMID: 32467321
DOI: 10.1136/jclinpath-2020-206527

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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