Article
The characteristics of the synonymous codon usage in hepatitis B virus and the effects of host on the virus in codon usage pattern.
Virology journal - 15 Dec 2011
Ma Ming-ren, Ha Xiao-qin, Ling Hui, Wang Mei-liang, Zhang Fang-xin, Zhang Shang-di, Li Ge, Yan Wei
Abstract excerpt
BACKGROUND: Hepatitis B virus (HBV) infection is one of the main human health problem and causes a large-scale of patients chronic infection worldwide.. As the replication of HBV depends on its host cell system, codon usage pattern for the viral gene might be susceptible to two main selections, namely mutation pressure and translation selection. In this case, a deeper investigation between HBV evolution and host...
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