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Article

Ultrasensitive digital quantification of cytokines and bacteria predicts septic shock outcomes

25 May 2020

Abstract excerpt

Abstract Quantification of pathogen and host biomarkers is essential for the diagnosis, monitoring, and treatment of infectious diseases. Here, we demonstrate sensitive and rapid quantification of bacterial load and cytokines from human biological samples to generate actionable hypotheses. Our digital assay measures IL-6 and TNF-α proteins, gram-negative (GN) and gram-positive (GP) bacterial DNA, and the...

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Share to Bacterial Identification and Susceptibility Testing
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Share to Sepsis Diagnosis and Treatment

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PMID: 32451375
DOI: 10.1038/s41467-020-16124-9

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