Article
Identification of single nucleotide pleomorphisms associated with periodontal disease in head and neck cancer irradiation patients by exome sequencing.
Oral surgery, oral medicine, oral pathology and oral radiology - 1 Jul 2020
Talevi Valentina, Wen Jia, Lalla Rajesh V, Brennan Michael T, Mougeot Farah B, Mougeot Jean-Luc C
Abstract excerpt
OBJECTIVE: Periodontal disease (PD) is a common oral complication in patients with head and neck cancer (HNC) undergoing radiation therapy (RT). Our objective was to identify candidate single nucleotide polymorphisms (SNPs) associated with PD in radiation-treated patients with HNC. STUDY DESIGN: DNA was extracted from the saliva of patients with HNC (n = 69) before RT. Clinical attachment loss (CAL) increment...
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