Article
Transcript isoform sequencing reveals widespread promoter-proximal transcriptional termination in Arabidopsis.
Nature communications - 22 May 2020
Thomas Quentin Angelo, Ard Ryan, Liu Jinghan, Li Bingnan, Wang Jingwen, Pelechano Vicent, Marquardt Sebastian
Abstract excerpt
RNA polymerase II (RNAPII) transcription converts the DNA sequence of a single gene into multiple transcript isoforms that may carry alternative functions. Gene isoforms result from variable transcription start sites (TSSs) at the beginning and polyadenylation sites (PASs) at the end of transcripts. How alternative TSSs relate to variable PASs is poorly understood. Here, we identify both ends of RNA molecules in...
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