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Detection of TP53 gene mutation in blood of breast cancer patients based on circulating tumor DNA and its application in prognosis.

Cellular and molecular biology (Noisy-le-Grand, France) - 15 Nov 2023

Lu Qiran, Wei Luxin, Cai Shenbin, Zhang Zhe, Zhang Lifeng

Abstract excerpt

This experiment was carried out to explore the application value of high throughput gene sequencing technology in detecting TP53 gene mutations in the blood of patients with breast cancer by detecting ctDNA gene mutations, and exploring the relationship between TP53 mutations and clinicopathological characteristics and prognosis of patients. The gene mutation of peripheral blood ctDNA and tissue paraffin DNA...

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PMID: 38015519
DOI: 10.14715/cmb/2023.69.11.30

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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