Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Increased Pathogenicity and Virulence of Middle East Respiratory Syndrome Coronavirus Clade B In Vitro and In Vivo.

Journal of virology - 16 Jul 2020

Wang Yanqun, Sun Jing, Li Xiaobo, Zhu Airu, Guan Wenda, Sun De-Qiang, Gan Mian, Niu Xuefeng, Dai Jun, Zhang Lu, Zhang Zhaoyong, Shi Yongxia, Huang Shuxiang, Mok Chris Ka Pun, Yang Zifeng, Wang Zhongfang, Tan Wenjie, Li Yimin, Chen Ling, Chen Rongchang, Peiris Malik, Zhong Nanshan, Zhao Jingxian, Huang Jicheng, Zhao Jincun

Abstract excerpt

Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe acute respiratory disease in humans. MERS-CoV strains from early epidemic clade A and contemporary epidemic clade B have not been phenotypically characterized to compare their abilities to infect cells and mice. We isolated the clade B MERS-CoV ChinaGD01 strain from a patient infected during the South Korean MERS outbreak in 2015 and compared...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coronavirus Infections
Share to Genome, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Host-Pathogen Interactions

Share to Interferon Type I

Share to Middle East Respiratory Syndrome Coronavirus

Share to T-Lymphocytes

Share to Virus Replication

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 32434886
DOI: 10.1128/JVI.00861-20
PMCID: PMC7375386

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased Pathogenicity and Virulence of Middle East Respiratory Syndrome Coronavirus Clade B In Vitro and In Vivo.PMID 32434886Read ↗

Complete Genome Sequence of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) from the First Imported MERS-CoV Case in ChinaSemantic proximity Read ↗

SARS-CoV-2 Variants of Concern Infect the Respiratory Tract and Induce Inflammatory Response in Wild-Type Laboratory MiceSemantic proximity Read ↗

SARS-CoV-2 variants of concern infect the respiratory tract and induce inflammatory response in wild-type laboratory miceSemantic proximity Read ↗

Genotype and phenotype of COVID-19: Their roles in pathogenesis.Semantic proximity Read ↗

Molecular pathology of emerging coronavirus infectionsSemantic proximity Read ↗

Virulence of Enterovirus A71 Fluctuates Depending on the Phylogenetic Clade Formed in the Epidemic Year and Epidemic Region.Semantic proximity Read ↗

Middle East respiratory syndrome coronavirus infection: virus-host cell interactions and implications on pathogenesisSemantic proximity Read ↗

Differential pathogenesis of SARS-CoV-2 variants of concern in human ACE2-expressing miceSemantic proximity Read ↗

Genetic, pathogenic, and antigenic characterization of GX-1, a novel infectious bronchitis virus genotype identified in South Korea.Semantic proximity Read ↗

Immunological and Pathological Peculiarity of Severe Acute Respiratory Syndrome Coronavirus 2 Beta VariantSemantic proximity Read ↗

Identification of an infectious bronchitis coronavirus strain exhibiting a classical genotype but altered antigenicity, pathogenicity, and innate immunity profile.Semantic proximity Read ↗

Evolution of Omicron lineage towards increased fitness in the upper respiratory tract in the absence of severe lung pathologySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.