Article
A large familial cluster and sporadic cases of frontal fibrosing alopecia in Brazil reinforce known human leucocyte antigen (HLA) associations and indicate new HLA susceptibility haplotypes.
Journal of the European Academy of Dermatology and Venereology : JEADV - 1 Oct 2020
Ramos P M, Garbers L E F M, Silva N S B, Castro C F B, Andrade H S, Souza A S, Castelli E C, Miot H A
Abstract excerpt
BACKGROUND: Frontal fibrosing alopecia (FFA) is a lymphocytic scarring alopecia whose worldwide incidence is rising. Environmental triggers combined with genetic predisposition represent one of the current hypotheses in FFA aetiology. Familial clusters are opportunities to investigate the genetic basis of diseases. OBJECTIVES: Assess human leucocyte antigen (HLA) genetic variability in a Brazilian sample of a...
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