Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Activating Transcription Factor 5 Promotes Neuroblastoma Metastasis by Inducing Anoikis Resistance

28 Nov 2023

Abstract excerpt

MYCN-amplified neuroblastoma often presents as a highly aggressive metastatic disease with a poor prognosis. Activating transcription factor 5 (ATF5) is implicated in neural cell differentiation and cancer cell survival. Here, we show that ATF5 is highly expressed in patients with stage 4 high-risk neuroblastoma, with increased expression correlating with a poorer prognosis. We demonstrated that ATF5 promotes the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endoplasmic Reticulum Stress and Disease
Share to Neuroblastoma Research and Treatments
Share to Signaling Pathways in Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38014922
DOI: 10.1158/2767-9764.crc-23-0154

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Activating Transcription Factor 5 Promotes Neuroblastoma Metastasis by Inducing Anoikis ResistancePMID 38014922Read ↗

PRMT1 promotes neuroblastoma cell survival through ATF5Semantic proximity Read ↗

Transcription factor activating protein 4 is synthetically lethal and a master regulator of MYCN-amplified neuroblastomaSemantic proximity Read ↗

MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4Semantic proximity Read ↗

Tumorigenic proteins upregulated in the MYCN-amplified IMR-32 human neuroblastoma cells promote proliferation and migrationSemantic proximity Read ↗

ALK pERKs up MYCN in neuroblastoma.Semantic proximity Read ↗

NT5DC2 promotes tumorigenicity of glioma stem-like cells by upregulating fynSemantic proximity Read ↗

Cell Survival Signaling in NeuroblastomaSemantic proximity Read ↗

The kinase ALK stimulates the kinase ERK5 to promote the expression of the oncogene MYCN in neuroblastomaSemantic proximity Read ↗

Selective destruction of glioblastoma cells by interference with the activity or expression of ATF5.Semantic proximity Read ↗

Targeting the Oncogenic Transcriptional Regulator MYB in Adenoid Cystic Carcinoma by Inhibition of IGF1R/AKT SignalingSemantic proximity Read ↗

Adenylate Kinase-4 Is a Marker of Poor Clinical Outcomes That Promotes Metastasis of Lung Cancer by Downregulating the Transcription Factor ATF3Semantic proximity Read ↗

The long non-coding RNA GAS5 differentially regulates cell cycle arrest and apoptosis through activation of BRCA1 and p53 in human neuroblastoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.