Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cannabis Constituents and Acetylcholinesterase Interaction: Molecular Docking, In Vitro Studies and Association with CNR1 rs806368 and ACHE rs17228602.

Biomolecules - 13 May 2020

Furqan Tiyyaba, Batool Sidra, Habib Rabia, Shah Mamoona, Kalasz Huba, Darvas Ferenc, Kuca Kamil, Nepovimova Eugenie, Batool Sajida, Nurulain Syed M

Abstract excerpt

The study documented here was aimed to find the molecular interactions of some of the cannabinoid constituents of cannabis with acetylcholinesterase (AChE). Molecular docking and LogP determination were performed to predict the AChE inhibitory effect and lipophilicity. AChE enzyme activity was measured in the blood of cannabis addicted human subjects. Further, genetic predisposition to cannabis addiction was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylcholinesterase
Share to Binding Sites

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cannabinoids

Share to Cholinesterase Inhibitors

Share to GPI-Linked Proteins

Share to Marijuana Abuse

Share to Molecular Docking Simulation

Share to Receptor, Cannabinoid, CB1

Source

Open in PubMed Open full text

Identifiers

PMID: 32414087
DOI: 10.3390/biom10050758
PMCID: PMC7277636

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cannabis Constituents and Acetylcholinesterase Interaction: Molecular Docking, In Vitro Studies and Association with CNR1 rs806368 and ACHE rs17228602.PMID 32414087Read ↗

Medicinal Cannabis - Potential Drug InteractionsSemantic proximity Read ↗

CNR1 gene polymorphisms in addictive disorders: a systematic review and a meta-analysis.Semantic proximity Read ↗

Pharmacogenetics of CannabinoidsSemantic proximity Read ↗

Cannabis induced psychosis: A systematic review on the role of genetic polymorphisms.Semantic proximity Read ↗

Predicted Net Effects of Drug-Gene Interactions on Levels of Tetrahydrocannabinol and CannabidiolSemantic proximity Read ↗

The implication of CNR1 gene's polymorphisms in the modulation of endocannabinoid system effects.Semantic proximity Read ↗

S100A10 identified in a genome-wide gene × cannabis dependence interaction analysis of risky sexual behaviours.Semantic proximity Read ↗

Genetic epidemiology of cannabis use, abuse and dependence: a comment on Agrawal and Lynskey (2006).Semantic proximity Read ↗

The genetics of cannabis involvement in humans: a genetic epidemiological perspective.Semantic proximity Read ↗

Genetic basis of cannabis use: a systematic review.Semantic proximity Read ↗

Pharmacogenetic association study of cannabis use in chronic painSemantic proximity Read ↗

Enzyme ChE, cholinergic therapy and molecular docking: Significant considerations and future perspectivesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.