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Article

Phosphoregulation provides specificity to biomolecular condensates in the cell cycle and cell polarity.

The Journal of cell biology - 6 Jul 2020

Gerbich Therese M, McLaughlin Grace A, Cassidy Katelyn, Gerber Scott, Adalsteinsson David, Gladfelter Amy S

Abstract excerpt

Biomolecular condensation is a way of organizing cytosol in which proteins and nucleic acids coassemble into compartments. In the multinucleate filamentous fungus Ashbya gossypii, the RNA-binding protein Whi3 regulates the cell cycle and cell polarity through forming macromolecular structures that behave like condensates. Whi3 has distinct spatial localizations and mRNA targets, making it a powerful model for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32399546
DOI: 10.1083/jcb.201910021
PMCID: PMC7337510

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