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Article

Ensemble positive unlabeled learning for disease gene identification.

PloS one - 1 Jan 2014

Yang Peng, Li Xiaoli, Chua Hon-Nian, Kwoh Chee-Keong, Ng See-Kiong

Abstract excerpt

An increasing number of genes have been experimentally confirmed in recent years as causative genes to various human diseases. The newly available knowledge can be exploited by machine learning methods to discover additional unknown genes that are likely to be associated with diseases. In particular, positive unlabeled learning (PU learning) methods, which require only a positive training set P (confirmed disease...

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PMID: 24816822
DOI: 10.1371/journal.pone.0097079
PMCID: PMC4016241

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