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Article

Direct Binding of Salicylic Acid to Pectobacterium N-Acyl-Homoserine Lactone Synthase.

ACS chemical biology - 17 Jul 2020

Joshi Janak Raj, Khazanov Netaly, Khadka Nirmal, Charkowski Amy O, Burdman Saul, Carmi Nir, Yedidia Iris, Senderowitz Hanoch

Abstract excerpt

Salicylic acid (SA) is a hormone that mediates systemic acquired resistance in plants. We demonstrated that SA can interfere with group behavior and virulence of the soft-rot plant pathogen Pectobacterium spp. through quorum sensing (QS) inhibition. QS is a population density-dependent communication system that relies on the signal molecule acyl-homoserine lactone (AHL) to synchronize infection. P. parmentieri...

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PMID: 32392032
DOI: 10.1021/acschembio.0c00185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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